Disparities in Guideline Concordant Statin Treatment in Individuals With Chronic Obstructive Pulmonary Disease.

TitleDisparities in Guideline Concordant Statin Treatment in Individuals With Chronic Obstructive Pulmonary Disease.
Publication TypeJournal Article
Year of Publication2023
AuthorsKrishnan JK, Mallya SG, Nahid M, Baugh AD, Han MLK, Aronson KI, Goyal P, Pinheiro LC, Banerjee S, Martinez FJ, Safford MM
JournalChronic Obstr Pulm Dis
Volume10
Issue4
Pagination369-379
Date Published2023 Oct 26
ISSN2372-952X
Abstract

RATIONALE: Cardiovascular disease (CVD) affects the prognosis of patients with chronic obstructive pulmonary disease (COPD). Black women with COPD have a disproportionate risk of CVD-related mortality, yet disparities in CVD prevention in COPD are unknown.

OBJECTIVES: We aimed to identify race-sex differences in the receipt of statin treatment for CVD prevention, and whether these differences were explained by factors influencing health care utilization in the REasons for Geographic And Racial Differences in Stroke (REGARDS) COPD study sub-cohort.

METHODS: We conducted a cross-sectional analysis among REGARDS Medicare beneficiaries with COPD. Our primary outcome was the presence of statin on in-home pill bottle review among individuals with an indication. Prevalence ratios (PR) for statin treatment among race-sex groups compared to White men were estimated using Poisson regression with robust variance. We then adjusted for covariates previously shown to impact health care utilization.

RESULTS: Of the 2032 members within the COPD sub-cohort with sufficient data, 1435 participants (19% Black women, 14% Black men, 28% White women, and 39% White men) had a statin indication. All race-sex groups were less likely to receive statins than White men in unadjusted models. After adjusting for covariates that influence health care utilization, Black women (PR 0.76, 95% confidence interval [CI] 0.67 to 0.86) and White women (PR 0.84 95% CI 0.76 to 0.91) remained less likely to be treated compared to White men.

CONCLUSIONS: All race-sex groups were less likely to receive statin treatment in the REGARDS COPD sub-cohort compared to White men. This difference persisted in women after controlling for individual health care utilization factors, suggesting structural interventions are needed.

DOI10.15326/jcopdf.2023.0395
Alternate JournalChronic Obstr Pulm Dis
PubMed ID37410623
PubMed Central IDPMC10699489
Grant ListR01 HL080477 / HL / NHLBI NIH HHS / United States
T32 HL134629 / HL / NHLBI NIH HHS / United States
U01 NS041588 / NS / NINDS NIH HHS / United States
T32-HL134629 / GF / NIH HHS / United States